David Pincus Cell and Molecular Biology
Papers from NSF QuBBE
S. Chowdhary, S. Paracha, L. Dyer, and D. Pincus, "Emergent 3D Genome Reorganization and Graded Gene Control from the Stepwise Assembly of Transcriptional Condensates", Cell Rep 45 117888 (2026)
L. Dyer, J.T. Krystosek, S.A. Martin, C. Williams, L. Chaney Winner, A. Ali, S. Chowdhary, and D. Pincus, "Chaperone Condensates Buffer the Heat Shock Response against Pleiotropic Inputs", bioRxiv 2026.07.30.740154 (2026)
D.W. McDonald, A. Dea, R. Sava, Y.J. Kim, L. Joos, D. Pincus, and M.L. Duennwald, "Mitochondrial Respiration Modulates Hsf1 Activation and the Heat Shock Response", bioRxiv 2026.05.07.723568 (2026)
A. Dea, Y. Lan, B.A. Doran, A. Ali, M.G. Igarashi, L. Dyer, V. Aksianiuk, D. Pincus, and A.S. Raman, "Physiological Architecture and Evolutionary Origins of Cellular Adaptability", bioRxiv 2026.04.10.717775 (2026)
A. Neferkara, A. Ali, and D. Pincus, "Cellquant: A Vibecoder's Guide to Image Analysis", bioRxiv 2026.03.09.710634 (2026)
S. Lee, S. Chakraborty, S. Kim, A. Ali, K. Mitra, M. Zajac, A. Brown, D. Pincus, and Y. Krishnan, "Organelles Harbour Ph Gradients", bioRxiv 2025.2012.2012.694065 (2025)
S. Lee, S. Chakraborty, S. Kim, A. Ali, K. Mitra, M. Zajac, A. Brown, D. Pincus, and Y. Krishnan, "Organelles Harbour Ph Gradients", bioRxiv 2025.2012. 2012.694065 (2025)
S. Chowdhary, S. Paracha, L. Dyer, and D. Pincus, "Emergent 3d Genome Reorganization from the Stepwise Assembly of Transcriptional Condensates", bioRxiv 2025.2002. 2023.639564 (2025)
R. Garde, A. Dea, M.F. Herwig, A. Ali, and D. Pincus, "Feedback Control of the Heat Shock Response by Spatiotemporal Regulation of Hsp70", J Cell Biol 223 e202401082 (2024)
A. Dea, and D. Pincus, "The Heat Shock Response as a Condensate Cascade", J Mol Biol 436 168642 (2024)
A. Ali, S. Paracha, and D. Pincus, "Preserve or Destroy: Orphan Protein Proteostasis and the Heat Shock Response", J Cell Biol 223 e202407123 (2024)
R. Garde, A. Singh, A. Ali, and D. Pincus, "Transcriptional Regulation of Sis1 Promotes Fitness but Not Feedback in the Heat Shock Response", Elife 12 e79444 (2023)
A. Ali, R. Garde, O.C. Schaffer, J.A.M. Bard, K. Husain, S.K. Kik, K.A. Davis, S. Luengo-Woods, M.G. Igarashi, D.A. Drummond, A.H. Squires, and D. Pincus, "Adaptive Preservation of Orphan Ribosomal Proteins in Chaperone-Dispersed Condensates", Nat Cell Biol 25 1691-1703 (2023)
R. Garde, A. Singh, A. Ali, and D. Pincus, "Induction of Sis1 Promotes Fitness but Not Feedback in the Heat Shock Response", bioRxiv 2022.2004. 2027.489698 (2022)
S. Chowdhary, A.S. Kainth, S. Paracha, D.S. Gross, and D. Pincus, "Inducible Transcriptional Condensates Drive 3d Genome Reorganization in the Heat Shock Response", Mol Cell 82 4386-4399 e4387 (2022)